https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Synthetic Routes to 3,4,5-Trihydroxypiperidines via Stereoselective and Biocatalysed Protocols, and Strategies to N- and O-Derivatisation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41388 Tue 02 Aug 2022 17:40:26 AEST ]]> Recent results from non-basic glycosidase inhibitors: How structural diversity can inform general strategies for improving inhibition potency https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52765 Thu 26 Oct 2023 14:39:03 AEDT ]]> Synthetic pathways to 3,4,5-trihydroxypiperidines from the chiral pool https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37093 Mon 17 Aug 2020 12:34:44 AEST ]]> Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39057 Fsp3 index natural-product analogues such as imino­sugars are of paramount importance in the investigation of their biological activities and reducing the use of protecting groups is an advantageous synthetic strategy. An iso­propyl­idene group was employed towards the synthesis of seven-membered ring imino­sugars and the title compound, C9H15N3O5, was crystallized as an inter­mediate, in which the THF ring is twisted and the dioxolane ring adopts an envelope conformation: the dihedral angle between the rings is 67.50 (13)°. In the crystal, the hydroxyl groups participate in O—H...(O,O) and O—H...N hydrogen-bonding inter­actions, which generate chains of mol­ecules propagating parallel to the a-axis direction. There is a notable non-classical C—H...O hydrogen bond, which cross-links the [100] chains into (001) sheets.]]> Mon 02 May 2022 15:27:38 AEST ]]>